Juvéderm Ultra and Juvederm Ultra Plus ™ Juvéderm® XC injectable gel is a “next-generation” hyaluronic acid (HA) dermal filler. The smooth consistency gel helps to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your "smile lines" or nasolabial folds (creases that run from the bottom of your nose to the corners of your mouth).